Tumours may occasionally regress spontaneously leaving
retinal scars, and parents of an affected child should be
examined carefully. Second malignancies occur in up to 15%
of survivors in familial cases. In addition to tumours of the
head and neck caused by local irradiation treatment, other
associated malignancies include sarcomas (particularly of the
femur), breast cancers, pinealomas and bladder carcinomas.
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